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Pharmaceutical GBL Gamma - Hydroxybutyrate GHB

Categories Pharmaceutical Raw Materials
Brand Name: Pharmlab
Model Number: CAS 96-48-0
Certification: ISO 9001, USP,GMP
Place of Origin: EMS,HKEMS,FEDEX,DHL,UPS,Aramex,ETC
MOQ: 100ml
Price: negotiation
Payment Terms: Western Union, MoneyGram, T/T, Bitcoin
Supply Ability: Mass in stock
Delivery Time: 3~5 work days
Packaging Details: Well disguised package ; Plastic drum with safe shipping
Product name:: Gamma-Hydroxybutyrate
Alias:: GBL; GHB
Appearance:: Clear colorless oily liquid
Whatsapp:: +8613027196769
Shipping method:: EMS,HKEMS,FEDEX,DHL,UPS,Aramex,ETC
Shipping policy:: 100% resend policy if parcel seized
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Pharmaceutical GBL Gamma - Hydroxybutyrate GHB


Legit Sell Pharmaceutical GBL Gamma-Hydroxybutyrate CAS 96-48-0 GHB Improving Sleep


Quick detail:


Product Name: gamma-Butyrolactone; GBL
CAS: 96-48-0
MF: C4H6O2
MW: 86.09
EINECS: 202-509-5
Chemical Properties: Clear colorless oily liquid with a pleasant odor

Product Categories: Pharmaceutical Intermediates;Heterocycles;Miscellaneous Reagents;Halogenated Heterocycles ,Thiophenes ,Thiazolines/Thiazolidines

Specification : Magic GBL with Magic effect

Usage: Gamma-butyrolactone is one kind of important fine chemicalintermediate, simultaneously also is one kind of performance fine highboiling point solvent, ideal antioxidant, plasticizer,extracting agent, absorbent, dispersing agent, solid stain, Coagulation Reagent.


1. GBL Magic Cleaner is a cleaning liquid ,has unique clean strength .
2. GBL is used to produce the GHB with NaOH . GHB has been classified as a Class C drug .
3. people take gamma butyrolactone (GBL) for improving sleep, athletic performance and sexual performance and pleasure. They also take it for relieving depression and stress, promoting clear thinking, prolonging life, causing relaxation, and releasing growth hormone. GBL is also used to trim fat and as a body- or muscle-builder. Some people take it as a recreational drug.


GBL/GHB Chemical information for reference :


Melting point−45 °C
Boiling point204-205 °C
density1.12 g/mL at 25 °C
vapor density3 (vs air)
vapor pressure1.5 mm Hg ( 20 °C)
FEMA3291
Refractive indexn20/D 1.436
Fp209 °F
Storage temp.2-8°C
Water SolubilityMISCIBLE
Merck13,1596
Stability:Stable. Hygroscopic. Incompatible with strong oxidizing agents, strong acids, strong bases, strong reducing agents.
CAS DataBase Reference96-48-0(CAS DataBase Reference)
NIST Chemistry Reference«gamma»-Butyrolactone(96-48-0)
EPA Substance Registry2(3H)-Furanone, dihydro-(96-48-0)

GBL description :


GBL is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water. GBL is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug for GHB, and it is used as a recreational intoxicant with effects similar to alcohol. :)


GBL is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium gamma-hydroxybutyrate, the sodium salt of gamma-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide, GBL can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.


GBL is rapidly converted into GHB by paraoxonase (lactonase) enzymes, found in the blood. Animals which lack these enzymes exhibit no effect from GBL. GBL is more lipophilic (fat soluble) than GHB, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences, GBL tends to be more potent and faster-acting than GHB, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than GHB.


GBL Application:


Gamma-butyrolactone is a highly soluble, non-toxic, safe and easy to use high boiling point solvent, used in petroleum processing as butadiene, aromatic, advanced grease extractor; used in the chemical fiber industry Acrylonitrile fiber spinning solvent, wool, nylon, acrylonitrile and other fiber dyeing auxiliaries. In organic synthesis, GBL is also widely used, it is the synthesis of α-pyrrolidone, N-methyl pyrrolidone, vinyl pyrrolidone, acetyl-γ-butyrolactone, cyclopropylamine and other raw materials, synthetic insecticides, weeding Agents, drug brain rehabilitation, ciprofloxacin, vitamin B1, chlorophyll and other intermediates. Also used in the synthesis of chlorophenoxy butyric acid herbicides, plant growth regulators.


Gamma-butyrolactone process studies :


1. Maleic anhydride hydrogenation method The process is the development of the 1970s advanced technology, with a hydrogenation reaction, in any proportion of production of tetrahydrofuran and γ-butyrolactone, the usual ratio is tetrachlorofuran: γ-butyrolactone = 3-4: 1. Production enterprises more, but small scale, an average of 300t / a. The production capacity of the total domestic production capacity of 30%.


2. 1,4-butanediol dehydrogenation reactor for the tube, filled with flake copper catalyst (zinc oxide as the carrier). The reaction temperature is controlled at 230-240 ° C. The reaction product of crude γ-butyrolactone was distilled under reduced pressure to obtain a finished product in a yield of 77% or more.


The preparation method is based on 1,4-butanediol as raw material, the first preheating, and hydrogen in the presence of copper catalyst reaction, the temperature control in the 230 ~ 240 ℃, to obtain crude γ-butyrolactone, vacuum distillation product.


At present, maleic anhydride has been obtained by hydrogenation of succinic anhydride, and then further hydrogenation dehydration products.



The ramification of GBL:


1. Can be hydrolyzed to produce γ-hydroxy butyric acid, can be used as a special plasticizer plastic, pharmaceutical intermediates;
2. Can be oxidized to produce succinic acid; reduced to 4-hydroxy butyraldehyde, and then reduced to 1,4-butanediol;
3. Can be condensed to produce α, α - dihydroxy ketone acetal;
4. Can react with CH3NH2 to form N-methyl-2-pyrrolidone;
5. Can generate tetrahydrofuran;
6. Can react with SO3 to form butyrolactone-α-sulfonic acid;

7. Can react with NaCN to form 2-piperidone;

8. Can react with CO to produce glutaric acid;
9. Can react with NaOH to produce 4,4 - oxo succinic acid;

10. Can react with Na2S to form thiolated succinic acid;

With NA2SO3 reaction to generate sodium γ-sulfobutyrate.



Chemical analysis data of GBL :


GBLIndustrial grade
Purity (GC, wt%)≥99.5
Purity (GC, wt%)≤0.05
Purity (GC, wt%)≤25
Purity (GC, wt%)1.125~1.135
Refractive index (@20degree)1.435~1.438

Best service Items:


1. Offer best quanlity and competitive price.

2. well experienced in delivering the parcels to you.

Discreet and tight safe packing for Customs pass guaranteed.

Delivery: priority to the use of DHL, TNT, FedEx, HKEMS, UPS,etc.

3. Full stock ensures prompt delivery.

4. Superior after-sales service.

Payment terms:Western Union, MoneyGram, T/T,Paypal,Bitcoin.

5. Safest and fastest delivery.

We have Adequate stock,and can arranged within 24hours when receive
the payment.Tracking numberwould be informed quickly after shipment.
We have special way could ship 0.01 kilo to 50 kilo products a time.
We offer melting powder into liquid service. And ship the liquid in special bottles.

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Injections can be made for you professionally.
By Pharmlab


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